Candida and Candidiasis - A review of Virulence Factors

Authors

  • Atyaf Saied Hamied

DOI:

https://doi.org/10.24126/jobrc.2021.15.2.606

Keywords:

Candida albicans, virulence factors, candidiasis

Abstract

   The occurrences of invasive candidiasis has increased over the previous few decades. Although Candida albicans considers as one of the most common species of organisms, that cause acquired fungal infections.

Candida albicans is an opportunistic fungal pathogen and inherent in as a lifelong, the yeast is present in healthy individuals as a commensal, and can reside harmlessly in human body. However, in immuno-compromised individuals, the fungus can invade tissues, producing superficial infections and, in severe cases, life-threatening systemic infections. This review wills emphasis on virulence factor of C. albicans including (adhesion, invasion, candida proteinase, and phenotypic switching and biofilm formation.

Invasive Fungal diseases are result in very high morbidity as well as up to 60% mortality for people with severely susceptible hosts. This review will illustrate briefly the virulence factors in Candida albicans.

 

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Published

2021-12-01

How to Cite

Hamied, A. S. (2021). Candida and Candidiasis - A review of Virulence Factors. Journal of Biotechnology Research Center, 15(2), 13–20. https://doi.org/10.24126/jobrc.2021.15.2.606

Issue

Vol. 15 No. 2 (2021): issues 2

Section

Research articles

License

This is an Open Access article distributed under the terms of the creative commons Attribution (CC BY) 4.0 license which permits unrestricted use, distribution, and reproduction in any medium or format, and to alter, transform, or build upon the material, including for commercial use, providing the original author is credited.